[12] Therefore rejoice, ye heavens, and ye that dwell in them. Woe to the inhabiters of the earth and of the sea! for the devil is come down unto you, having great wrath, because he knoweth that he hath but a short time. Revelation 12:12.

I must confess that, since large segments of the this 12th chapter are parenthetical to the entire book, this may be associated with the three woes that begin with the blowing of the fifth trumpet, and end with the blowing of the seventh trumpet.  It may be that the wrath of the devil is poured out on man during this period, while God’s wrath is associated with the seven vials of wrath that follow.

[13] And I beheld, and heard an angel flying through the midst of heaven, saying with a loud voice, Woe, woe, woe, to the inhabiters of the earth by reason of the other voices of the trumpet of the three angels, which are yet to sound! [1] And the fifth angel sounded, and I saw a star fall from heaven unto the earth: and to him was given the key of the bottomless pit. [2] And he opened the bottomless pit; and there arose a smoke out of the pit, as the smoke of a great furnace; and the sun and the air were darkened by reason of the smoke of the pit. Revelation 8:13 & 9:2.

[1] And I heard a great voice out of the temple saying to the seven angels, Go your ways, and pour out the vials of the wrath of God upon the earth. Revelation 16:1.

While rejoicing is going on in heaven, because of the permanent removal of the devil, three great woes are being experienced by “the inhabitants of the earth” due to his presence among them.   The devil pours out his wrath at an accelerated rate because he knows he only has a short time to vent his anger.  Revelation 12:13 returns us to be troubles of a small section of mankind – the surviving one-third of the nation of Israel trapped in the Negev wilderness.   

[13] And when the dragon saw that he was cast unto the earth, he persecuted the woman which brought forth the man child. Revelation 12:13.

The woman is what remains of Israel after the attack that drove her into the Negev and conquered Jerusalem.  If the attack were to occur in the next three years, it would amount to some 1.7 to 1.9 million Israelis.

[8] And it shall come to pass, that in all the land, saith the Lord, two parts therein shall be cut off and die; but the third shall be left therein. [9] And I will bring the third part through the fire, and will refine them as silver is refined, and will try them as gold is tried: they shall call on my name, and I will hear them: I will say, It is my people: and they shall say, The Lord is my God. [1] Behold, the day of the Lord cometh, and thy spoil shall be divided in the midst of thee. [2] For I will gather all nations against Jerusalem to battle; and the city shall be taken, and the houses rifled, and the women ravished; and half of the city shall go forth into captivity, and the residue of the people shall not be cut off from the city. Zechariah 13:8 to 14:2.